PBLI1 Evidence-based and informed practice
A short summary in PICUlearn's own words. The original wording is in the publisher's document.
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Videos
- Pediatric Surviving Sepsis: Insights From the Leadership by M. Peters, S. Weiss | OPENPediatricsOPENPediatricsVideo
- Pediatric End-of-Life Guidelines & Insights by D. DeCourcey and S. Derrington | OPENPediatricsOPENPediatricsVideo
- Critical Content: Pediatric Critical Care Medicine, July 2026SCCMVideo
- Pediatric ECMO Cannulation Strategies in Refractory Septic Shock by G. MacLaren | OPENPediatricsOPENPediatricsVideo
- Why Prone Positioning Failed in Children | The Curley Trial Explained in 90 SecondsPICU ReviewVideo
- What is the role of prone positioning in pediatric ARDS? Dr Martin KneyberAll about newborn care!Video
- Critical Content: Pediatric Critical Care Medicine, September 2026SCCMVideo
- National Estimates of Pediatric Sepsis by F. Balamuth and C. Rhee | OPENPediatricsOPENPediatricsVideo
- Fostering a Culture of Research in Children's Critical CareUCD School of Nursing, Midwifery & Health SystemsVideo
- Endotracheal Suctioning: What do We Really Know? by M. Pedreira | OPENPediatricsOPENPediatricsVideo
- Book a Date to RENOVATESCCMVideo
- PEDICRITICON 2025: Top Articles in PICU Research by A. Agarwal and R. Rameshkumar | OPENPediatricsOPENPediatricsVideo
- Choosing the Right Support –A Debate on HHFNC vs NIVWFPICCSVideo
- Critical Content: Pediatric Critical Care Medicine, August 2026SCCMVideo
- Evidence in Nutrition Practice: Global Practices in Pediatric Intensive Care Units - Channel ONEBaxter Non-Promotional Medical Education HubVideo
- Critical Content: Pediatric Critical Care Medicine, June 2026SCCMVideo
Guidelines and evidence
- Inotropes for the prevention of low cardiac output syndrome and mortality for paediatric patients undergoing surgery for congenital heart disease: a network meta-analysis.Cochrane, 2024Guideline or evidence
- Association Between Adherence to Guidelines and Patient Outcomes in Severe Pediatric Traumatic Brain Injury: A Scoping Review.Journal of Neurotrauma, 2025Guideline or evidence
- 2022 Society of Critical Care Medicine Clinical Practice Guidelines on Prevention and Management of Pain, Agitation, Neuromuscular Blockade, and Delirium in Critically Ill Pediatric Patients With Consideration of the ICU Environment and Early Mobility.Society of Critical Care Medicine (SCCM), 2022Guideline or evidence
- Red blood cell transfusion threshold after pediatric cardiac surgery: A systematic review and meta-analysis.Medicine (journal), 2019Guideline or evidence
- Adapting Evidence-Based Practice Guidelines for Sedation, Analgesia, Withdrawal, and Delirium Assessment and Management in Critically Ill Children.Critical Care Research and Practice (institutional guideline adaptation panel), 2026Guideline or evidence
- 2023 International Consensus on Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science With Treatment Recommendations: Summary From the Basic Life Support; Advanced Life Support; Pediatric Life Support; Neonatal Life Support; Education, Implementation, and Teams; and First Aid Task Forces.International Liaison Committee on Resuscitation (ILCOR), 2023Guideline or evidence
- Role of vasopressin and terlipressin in refractory shock compared to conventional therapy in the neonatal and pediatric population: a systematic review, meta-analysis, and trial sequential analysis.Critical Care (BioMed Central), 2017Guideline or evidence
- Impact of Delirium on Pediatric Critical Care Outcomes and Management Strategies: A Systematic Review and Meta-Analysis.Journal of Nursing Management, 2026Guideline or evidence
- What is the New Research in Pediatric Critical Illness-Related Delirium Since the 2022 Clinical Practice Guidelines.Pediatric Critical Care Medicine (SCCM/WFPICCS journal), 2025Guideline or evidence
- Outcomes of Delaying Parenteral Nutrition for 1 Week vs Initiation Within 24 Hours Among Undernourished Children in Pediatric Intensive Care: A Subanalysis of the PEPaNIC Randomized Clinical Trial.JAMA Network Open, 2018Guideline or evidence
- Guidelines for the management of emergencies and critical illness in pediatric and adult patients with sickle cell disease.Annals of Intensive Care (French expert panel), 2025Guideline or evidence
- Measuring evidence-based clinical guideline compliance in the paediatric intensive care unit.BMJ Open Quality, 2024Guideline or evidence
- Efficacy and safety of levetiracetam for pediatric convulsive status epilepticus in emergency settings: a systematic review and meta-analysis.BMC Neurology, 2025Guideline or evidence
- Levetiracetam versus phenytoin for second-line treatment of paediatric convulsive status epilepticus (EcLiPSE): a multicentre, open-label, randomised trial.Lancet (NIHR HTA-funded EcLiPSE trial), 2019Guideline or evidence
- Association of Arterial Hyperoxia With Outcomes in Critically Ill Children: A Systematic Review and Meta-analysis.JAMA Network Open, 2022Guideline or evidence
- A systematic review and quality analysis of pediatric traumatic brain injury clinical practice guidelines.PLoS One, 2018Guideline or evidence
- ESPNIC clinical practice guidelines: intravenous maintenance fluid therapy in acute and critically ill children- a systematic review and meta-analysis.ESPNIC, 2022Guideline or evidence
- A randomized trial of Plasma-Lyte A and 0.9 % sodium chloride in acute pediatric gastroenteritis.BMC Pediatrics, 2016Guideline or evidence
- The Infant KIdney Dialysis and Utrafiltration (I-KID) Study: A Stepped-Wedge Cluster-Randomized Study in Infants, Comparing Peritoneal Dialysis, Continuous Venovenous Hemofiltration, and Newcastle Infant Dialysis Ultrafiltration System, a Novel Infant Hemodialysis Device.Pediatric Critical Care Medicine (SCCM/WFPICCS), 2023Guideline or evidence
- Tight glycemic control in critically ill pediatric patients: a systematic review and meta-analysis.Critical Care (BioMed Central), 2018Guideline or evidence
- Balanced crystalloid versus saline for resuscitation in pediatric septic shock: a systematic review and meta-analysis.BMC Pediatrics, 2025Guideline or evidence
- Management of asthma exacerbations in the paediatric population: a systematic review.European Respiratory Review (European Respiratory Society), 2021Guideline or evidence
- UPDATE - 2022 Italian guidelines on the management of bronchiolitis in infants.Italian Society of Pediatrics (Italian Journal of Pediatrics), 2023Guideline or evidence
- Efficacy and safety of high flow nasal oxygen for children with bronchiolitis: systematic review and meta-analysis.BMJ Open Respiratory Research, 2021Guideline or evidence
- Trends Over Time in Use of Nonrecommended Tests and Treatments Since Publication of the American Academy of Pediatrics Bronchiolitis Guideline.JAMA Network Open, 2021Guideline or evidence
- SABRE: a multicentre randomised control trial of nebulised hypertonic saline in infants hospitalised with acute bronchiolitis.Thorax (SABRE trial investigators, UK), 2014Guideline or evidence
- Association of Extubation Failure Rates With High-Flow Nasal Cannula, Continuous Positive Airway Pressure, and Bilevel Positive Airway Pressure vs Conventional Oxygen Therapy in Infants and Young Children: A Systematic Review and Network Meta-Analysis.JAMA Pediatrics, 2023Guideline or evidence
- Randomised controlled trial of oxygen therapy and high-flow nasal therapy in African children with pneumonia.Intensive Care Medicine (COAST trial investigators), 2021Guideline or evidence
- Safety and efficacy of pulmonary surfactant therapy for acute respiratory distress syndrome in children: a systematic review and meta-analysis.BMC Pulmonary Medicine, 2025Guideline or evidence
- A systematic review of clinical practice guidelines and recommendations for the management of pain, sedation, delirium and iatrogenic withdrawal syndrome in pediatric intensive care.Frontiers in Pediatrics, 2023Guideline or evidence
- A randomized controlled trial of daily sedation interruption in critically ill children.Intensive Care Medicine, 2016Guideline or evidence
- Daily Sedation Interruption vs Continuous Sedation in Pediatric Patients Receiving Mechanical Ventilation: A Systematic Review and Meta-analysis.JAMA Network Open, 2024Guideline or evidence