Evidence · Systematic review or meta-analysis
Red blood cell transfusion threshold after pediatric cardiac surgery: A systematic review and meta-analysis.
- Blood products
- Cardiovascular
- Congenital heart disease
- Haematology and oncology
- Medical
- Nursing
This paper is from 2019, more than five years ago. Newer evidence may have been published since.
Summary
Systematic review and meta-analysis of four randomised controlled trials (454 patients) comparing restrictive versus liberal red blood cell transfusion thresholds after paediatric cardiac surgery. Outcomes assessed included ICU and hospital length of stay, duration of ventilation, arterial lactate and mortality, with no significant differences found between strategies. The authors conclude restrictive thresholds appear non-inferior, but the evidence base is limited and further high-quality trials are needed. Relevant to PICU teams managing postoperative congenital cardiac patients and transfusion decision-making.
Summary written for PICUlearn. Always read the original.
- Licence:
- Open (Creative Commons)
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