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Adapting Evidence-Based Practice Guidelines for Sedation, Analgesia, Withdrawal, and Delirium Assessment and Management in Critically Ill Children.

Critical Care Research and Practice (institutional guideline adaptation panel)2026Full text
  • Care and rehabilitation
  • Delirium
  • Early mobilisation
  • Mechanical ventilation
  • Medical
  • Nursing
  • Pain management
  • Physiotherapy
  • Respiratory
  • Sedation
  • Sedation and analgesia

Summary

This paper describes the adaptation of existing evidence-based clinical practice guidelines for sedation, analgesia, iatrogenic withdrawal and delirium in critically ill children, with an emphasis on early mobility. A multidisciplinary adaptation panel and external reviewers followed a formal three-phase adaptation methodology. Outputs include assessment tools (behavioural sedation/pain scoring, a withdrawal assessment tool, a delirium screening score) and algorithms for sedation, analgesia and weaning in both non-invasive and invasively ventilated patients. It is intended to standardise PICU practice, with further work needed on generalisability and implementation barriers.

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Open (Creative Commons)

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