2.E Inflammatory, immune and infectious disease
A short summary in PICUlearn's own words. The original wording is in the publisher's document.
- 2.E.1 Sepsis and associated conditions
- 2.E.2 Infections and infectious syndromes
- 2.E.3 Transplantation medicine
- 2.E.4 Autoimmune and inflammatory disease
- 2.E.5 Primary and acquired immunodeficiency
- 2.E.6 Other immune and post-infectious syndromes, including anaphylaxis
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Course modules
Videos
- Shock, Septic Shock & Inotropes | Pediatrics PG Residency | Dr. Parag Shankarrao | DocTutorialsDocTutorials Super SpecialityVideo
- (Bacterial) Meningitis PathophysiologyArmando HasudunganVideo
- Pediatric Surviving Sepsis: Insights From the Leadership by M. Peters, S. Weiss | OPENPediatricsOPENPediatricsVideo
- Raised Intracranial Pressure & Central Nervous System Infections by S. Singhi | OPENPediatricsOPENPediatricsVideo
- QPS TalkTime Ep.23: A spotlight on sepsis in infants and childrenHSE National QPSVideo
- Meningitis - Medical-Surgical - Nervous System | @LevelUpRNLevel Up RNVideo
- Pediatric Septic Shock by J. O'Hara and K. Madden | OPENPediatricsOPENPediatricsVideo
- National Estimates of Pediatric Sepsis by F. Balamuth and C. Rhee | OPENPediatricsOPENPediatricsVideo
- Meningitis - causes, symptoms, diagnosis, treatment, pathologyOsmosis from ElsevierVideo
- Meningitis Nursing Neuro NCLEX Review: Meningitis Causes, Symptoms, Treatment VaccineRegisteredNurseRNVideo
- Understanding Sepsis (Sepsis Explained Clearly)Rhesus MedicineVideo
- Meningitis - Pediatric Nursing - Nervous System Disorders | @LevelUpRNLevel Up RNVideo
- Clinical Perspectives on Refractory Shock Management: Vasopressor Strategy, Perfusion, & EscalationSCCMVideo
- Pediatric Sepsis Updates and Changes at UHS Pediatric Grand Rounds 2 27 2026 Meeting RecordingUniversity of Texas Health Science Center at San Antonio - UT Health San AntonioVideo
- SepsisPaediatric EmergenciesVideo
- Pediatric Sepsis | Pediatric Grand Round - Mattel Children's Hospital UCLADavid Geffen School of Medicine at UCLAVideo
Guidelines and evidence
- Rethinking Pediatric Sepsis and Septic Shock: Beyond International Consensus Criteria.Pediatric Health, Medicine and Therapeutics (expert commentary), 2025Guideline or evidence
- Prospective Evaluation of Adherence to French Guidelines on Early Onset Sepsis Management.The Pediatric Infectious Disease Journal, 2025Guideline or evidence
- Pocket book of hospital care for children: guidelines for the management of common childhood illnessesWorld Health Organization, 2013Guideline or evidence
- Adherence to surviving sepsis guidelines among pediatric intensivists. A national survey.Saudi Medical Journal, 2017Guideline or evidence
- Clinical characteristics, treatment and outcomes of paediatric COVID-19: a systematic review and meta-analysis.Archives of Disease in Childhood (BMJ), 2021Guideline or evidence
- [Interpretation on the "surviving sepsis campaign international guidelines for the management of septic shock and sepsis-associated organ dysfunction in children"].Chinese Journal of Contemporary Pediatrics, 2020Guideline or evidence
- Clinical guideline highlights for the hospitalist: International consensus criteria for pediatric sepsis and septic shock.Society of Critical Care Medicine (Phoenix criteria), 2024Guideline or evidence
- Development and validation of a diagnostic model for early differentiation of sepsis and non-infectious SIRS in critically ill children - a data-driven approach using machine-learning algorithms.BMC Pediatrics, 2018Guideline or evidence
- Manual on paediatric HIV care and treatment for district hospitals: addendum to the Pocket book of hospital care of childrenWorld Health Organization, 2011Guideline or evidence
- Suspected sepsis: recognition, diagnosis and early management (NICE guideline NG51)NICE, 2024Guideline or evidence
- Surviving Sepsis Campaign International Guidelines for the Management of Septic Shock and Sepsis-Associated Organ Dysfunction in Children.Surviving Sepsis Campaign (SCCM/ESICM), 2020Guideline or evidence
- Guideline on management of pneumonia and diarrhoea in children up to 10 years of ageWorld Health Organization, 2024Guideline or evidence
- Role of extracorporeal membrane oxygenation in children with sepsis: a systematic review and meta-analysis.Critical Care (BioMed Central), 2020Guideline or evidence
- Candida thrombophlebitis in children: a systematic review of the literature.Italian Journal of Pediatrics, 2020Guideline or evidence
- COVID-19 PICU guidelines: for high- and limited-resource settings.International PICU COVID-19 Collaboration (Pediatric Research), 2020Guideline or evidence
- SEVERE PERTUSSIS IN CHILDHOOD: UPDATE AND CONTROVERSY - SYSTEMATIC REVIEW.Revista Paulista de Pediatria (Sociedade de Pediatria de São Paulo), 2019Guideline or evidence
- International Consensus Recommendations for the Treatment of Pediatric NMDAR Antibody Encephalitis.International NMDARE Consensus Panel (Neurology: Neuroimmunology & Neuroinflammation), 2021Guideline or evidence
- Neurological complications in pediatric patients with SARS-CoV-2 infection: a systematic review of the literature.Italian Journal of Pediatrics, 2021Guideline or evidence
- Implementing Pediatric Surviving Sepsis Campaign Guidelines: Improving Compliance With Lactate Measurement in the PICU.Critical Care Explorations, 2023Guideline or evidence
- Early resuscitation of dengue shock syndrome in children with hyperosmolar sodium-lactate: a randomized single-blind clinical trial of efficacy and safety.Critical Care (BioMed Central), 2014Guideline or evidence
- Pertussis infection in critically ill infants: meta-analysis and validation of a mortality score.Critical Care (London, England), 2025Guideline or evidence
- Balanced crystalloid versus saline for resuscitation in pediatric septic shock: a systematic review and meta-analysis.BMC Pediatrics, 2025Guideline or evidence
- Expert consensus on the diagnosis, treatment, and prevention of respiratory syncytial virus infections in children.World Journal of Pediatrics (multidisciplinary expert consensus group), 2024Guideline or evidence
- Systematic review and meta-analysis of the prevalence of common respiratory viruses in children < 2 years with bronchiolitis in the pre-COVID-19 pandemic era.PLoS One, 2020Guideline or evidence
- The role of viral co-infections in the severity of acute respiratory infections among children infected with respiratory syncytial virus (RSV): A systematic review and meta-analysis.Journal of Global Health, 2020Guideline or evidence
- Monoclonal Antibody for the Prevention of Respiratory Syncytial Virus in Infants and Children: A Systematic Review and Network Meta-analysis.JAMA Network Open, 2023Guideline or evidence
- Risk Factors for Severe COVID-19 in Children: A Systematic Review and Meta-Analysis.Journal of Korean Medical Science, 2022Guideline or evidence
- Permissive versus restrictive temperature thresholds in critically ill children with fever and infection: a multicentre randomized clinical pilot trial.Critical Care (BioMed Central), 2019Guideline or evidence