Evidence · Systematic review or meta-analysis
Neurological complications in pediatric patients with SARS-CoV-2 infection: a systematic review of the literature.
- Infection and sepsis
- Medical
- Meningitis and encephalitis
- Neurology
- Nursing
- Raised intracranial pressure
Summary
This systematic review collates 44 published articles describing 59 paediatric cases of neurological involvement associated with SARS-CoV-2 infection, including an additional case of acute disseminated encephalomyelitis. Most cases arose in the context of multisystem inflammatory syndrome in children, with cerebrovascular events, reversible splenial lesions, Guillain-Barré syndrome, benign intracranial hypertension and meningoencephalitis also described. Imaging was performed in most cases and CSF viral detection was rare; outcomes were largely favourable. Useful background for PICU teams assessing children with neurological presentations during or after COVID-19.
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- Licence:
- Open (Creative Commons)
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