Evidence · Systematic review or meta-analysis
Clinical characteristics, treatment and outcomes of paediatric COVID-19: a systematic review and meta-analysis.
- Cardiovascular
- Infection and sepsis
- Medical
- Nursing
- Respiratory
- Sepsis
- Shock
Summary
Systematic review and meta-analysis of 129 observational studies covering 10 251 children with laboratory-confirmed COVID-19 from 31 countries. It pools clinical features, investigations, treatments and outcomes, comparing them by World Bank country income level and by disease severity, including a subgroup analysis of multisystem inflammatory syndrome in children. Findings include a generally favourable prognosis, lower intensive care admission but higher case fatality among hospitalised children in low- and middle-income countries, and greater ICU use and mortality in MIS-C. Useful background for PICU staff managing paediatric COVID-19 and MIS-C presentations.
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- Licence:
- Open (Creative Commons)
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