Guideline · Consensus statement
International Consensus Recommendations for the Treatment of Pediatric NMDAR Antibody Encephalitis.
- Infection and sepsis
- Medical
- Meningitis and encephalitis
- Neurology
- Nursing
Summary
Delphi-derived international consensus recommendations on immunotherapy for paediatric NMDA receptor antibody encephalitis. Covers first-line corticosteroids with immunoglobulin or plasma exchange in severe disease, escalation to second-line agents such as rituximab or cyclophosphamide, further escalation options, maintenance therapy, relapse management and post-herpes simplex cases, plus definitions of severity, failure to improve and relapse. Also addresses total treatment duration by clinical course and timing of tumour screening. Useful to PICU teams managing severely affected children with encephalitis requiring critical care support.
Summary written for PICUlearn. Always read the original.
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- Open (Creative Commons)
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