LO4-1 Use of anaesthetic, sedative, analgesic and paralysing drugs
A short summary in PICUlearn's own words. The original wording is in the publisher's document.
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Course modules
Videos
- Sedatives & Analgesics for Intubation by R. Pascucci | OPENPediatricsOPENPediatricsVideo
- KeepMeSafe Workshop: Pain and Sedation in Paediatric critical careBSAPCHVideo
- Cardiac RESTORE:Protocolized Sedation and Weaning for Pediatrics by P.Lincoln, et al |OPENPediatricsOPENPediatricsVideo
- Procedural Sedation and Analgesia in Children by E. Fleegler | OPENPediatricsOPENPediatricsVideo
- Sedation in ICU Patients (Part 1) - ICU DripsICU AdvantageVideo
- SCCMPod-572: Propofol in the ICU: Balancing Sedation and StabilitySCCMVideo
- Sedation Safety by D. Fagin | OPENPediatricsOPENPediatricsVideo
Guidelines and evidence
- Supporting clinical guidelines for opioid conversion to methadone and tapering to prevent withdrawal in critically ill children using physiology based pharmacokinetic modeling and simulation.PLoS One (Dutch Pediatric Formulary expert panel), 2026Guideline or evidence
- 2022 Society of Critical Care Medicine Clinical Practice Guidelines on Prevention and Management of Pain, Agitation, Neuromuscular Blockade, and Delirium in Critically Ill Pediatric Patients With Consideration of the ICU Environment and Early Mobility.Society of Critical Care Medicine (SCCM), 2022Guideline or evidence
- Adapting Evidence-Based Practice Guidelines for Sedation, Analgesia, Withdrawal, and Delirium Assessment and Management in Critically Ill Children.Critical Care Research and Practice (institutional guideline adaptation panel), 2026Guideline or evidence
- A systematic review of dexmedetomidine pharmacology in pediatric patients.Clinical and Translational Science, 2024Guideline or evidence
- Adherence to Sedation Protocol Recommendations in Intubated ICU Patients.Pediatric Critical Care Medicine (SCCM/WFPICCS), 2026Guideline or evidence
- A systematic review of clinical practice guidelines and recommendations for the management of pain, sedation, delirium and iatrogenic withdrawal syndrome in pediatric intensive care.Frontiers in Pediatrics, 2023Guideline or evidence
- Clinical recommendations for pain, sedation, withdrawal and delirium assessment in critically ill infants and children: an ESPNIC position statement for healthcare professionals.ESPNIC, 2016Guideline or evidence
- Is There Any Dose of Benzodiazepines Safe for Delirium in the PICU? A Secondary Analysis of the PICU Up! Pilot Trial Dataset.Critical Care Explorations (PICU Up! trial investigators), 2026Guideline or evidence
- Practice guidelines for sedation and analgesia management of critically ill children: a pilot study evaluating guideline impact and feasibility in the PICU.BMJ Open, 2015Guideline or evidence
- A randomized controlled trial of daily sedation interruption in critically ill children.Intensive Care Medicine, 2016Guideline or evidence
- Daily Sedation Interruption vs Continuous Sedation in Pediatric Patients Receiving Mechanical Ventilation: A Systematic Review and Meta-analysis.JAMA Network Open, 2024Guideline or evidence