3.B Pharmacology of sedatives, analgesics and paralytics
A short summary in PICUlearn's own words. The original wording is in the publisher's document.
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Course modules
Videos
- Sedatives & Analgesics for Intubation by R. Pascucci | OPENPediatricsOPENPediatricsVideo
- Procedural Sedation and Analgesia in Children by E. Fleegler | OPENPediatricsOPENPediatricsVideo
- Pediatric Pain Management in the Emergency Department by C. Chumpitazi | OPENPediatricsOPENPediatricsVideo
- SCCMPod-572: Propofol in the ICU: Balancing Sedation and StabilitySCCMVideo
Guidelines and evidence
- Supporting clinical guidelines for opioid conversion to methadone and tapering to prevent withdrawal in critically ill children using physiology based pharmacokinetic modeling and simulation.PLoS One (Dutch Pediatric Formulary expert panel), 2026Guideline or evidence
- 2022 Society of Critical Care Medicine Clinical Practice Guidelines on Prevention and Management of Pain, Agitation, Neuromuscular Blockade, and Delirium in Critically Ill Pediatric Patients With Consideration of the ICU Environment and Early Mobility.Society of Critical Care Medicine (SCCM), 2022Guideline or evidence
- A systematic review of dexmedetomidine pharmacology in pediatric patients.Clinical and Translational Science, 2024Guideline or evidence
- Efficacy and safety of dexmedetomidine in maintaining hemodynamic stability in pediatric cardiac surgery: a systematic review and meta-analysis.Jornal de Pediatria, 2022Guideline or evidence
- Is There Any Dose of Benzodiazepines Safe for Delirium in the PICU? A Secondary Analysis of the PICU Up! Pilot Trial Dataset.Critical Care Explorations (PICU Up! trial investigators), 2026Guideline or evidence
- Turkish Neonatal Society guideline on the neonatal pain and its management.Turkish Neonatal Society, 2018Guideline or evidence
- Evidence-based practical guideline for procedural pain management and sedation for burn pediatrics patients undergoing wound care procedures.Annals of Medicine and Surgery, 2022Guideline or evidence