Evidence · Systematic review or meta-analysis
Efficacy and safety of dexmedetomidine in maintaining hemodynamic stability in pediatric cardiac surgery: a systematic review and meta-analysis.
- Arrhythmias
- Cardiovascular
- Congenital heart disease
- Medical
- Nursing
- Sedation
- Sedation and analgesia
Summary
A systematic review and meta-analysis of 15 randomised controlled trials examining dexmedetomidine use for haemodynamic stability during and after paediatric cardiac surgery. Outcomes assessed included systolic, diastolic and mean arterial pressures, heart rate, and adverse events. The authors report reductions in heart rate and a lower frequency of junctional ectopic tachycardia in dexmedetomidine-treated children compared with placebo. Relevant to PICU teams caring for postoperative congenital cardiac patients requiring sedation.
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- Licence:
- Open (Creative Commons)
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