Evidence · Systematic review or meta-analysis
Risk factors for healthcare-associated infection and colonization of Serratia marcescens in neonates: a systematic review and meta-analysis.
- Infection and sepsis
- Infection prevention
- Line and device care
- Medical
- Nursing
Summary
Systematic review and meta-analysis of 12 studies identifying risk factors for Serratia marcescens infection and colonisation in neonates, mostly in NICU settings. Prematurity and very low birth weight were key host factors, while invasive devices (enteral tubes, arterial and central venous catheters, CPAP, mechanical ventilation, surgery) and antibiotic exposure increased risk; breastfeeding and vaginal delivery appeared protective. The authors argue for targeted infection prevention and control measures including antimicrobial stewardship and device care. Evidence is limited by predominantly case-control designs.
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- Licence:
- Open (Creative Commons)
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