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Evidence · Research paper

Restrictive guideline for red blood cell transfusions in preterm neonates: effect of a protocol change.

Research paperVox Sanguinis2019Over 5 years oldFull text
  • Blood products
  • Haematology and oncology
  • Medical
  • Nursing

This paper is from 2019, more than five years ago. Newer evidence may have been published since.

Summary

This observational before-and-after study examined red blood cell transfusion practice in preterm neonates following introduction of a more restrictive transfusion protocol. Fewer neonates were transfused and the mean number of transfusions per transfused infant fell after the change, with no observed association with short-term outcomes or mortality. It supports restrictive transfusion thresholds in neonatal care, an approach with parallels in paediatric intensive care transfusion practice.

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