Evidence · Randomised trial
Furosemide versus ethacrynic acid in pediatric patients undergoing cardiac surgery: a randomized controlled trial.
- Acute kidney injury
- Cardiovascular
- Congenital heart disease
- Fluids and electrolytes
- Medical
- Nursing
- Renal and metabolic
This paper is from 2015, more than five years ago. Newer evidence may have been published since.
Summary
A prospective double-blinded randomised controlled trial comparing continuous infusions of furosemide and ethacrynic acid in infants after congenital heart surgery. Outcomes included urine output, fluid balance, renal, cardiac, respiratory and metabolic effects. Ethacrynic acid produced greater urine output on the day of surgery at lower dose, with more marked metabolic alkalosis, and was associated with better cardiac index and shorter ventilation and cardiac ICU stay. Relevant to diuretic strategy in the postoperative paediatric cardiac patient.
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- Licence:
- Open (Creative Commons)
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