Evidence · Randomised trial
Effects of colloid pre-loading on thromboelastography during elective intracranial tumor surgery in pediatric patients: hydroxyethyl starch 130/0.4 versus 5% human albumin.
- Blood products
- Fluids and electrolytes
- Haematology and oncology
- Medical
- Neurology
- Oncology emergencies
- Raised intracranial pressure
- Renal and metabolic
This paper is from 2017, more than five years ago. Newer evidence may have been published since.
Summary
A randomised controlled trial comparing 6% hydroxyethyl starch 130/0.4 with 5% human albumin as pre-load volume therapy in 60 children undergoing elective intracranial tumour resection. Coagulation was assessed by thromboelastography alongside haemodynamic and haematological parameters, transfusion, fluid balance, ICU and hospital stay. The authors report no significant between-group differences in TEG-assessed coagulation or clinical outcomes, other than a transient fall in maximum amplitude after infusion. Of interest to PICU teams receiving post-operative neurosurgical children and considering colloid choice for volume replacement.
Summary written for PICUlearn. Always read the original.
- Licence:
- Open (Creative Commons)
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