Evidence · Systematic review or meta-analysis
Neurally Adjusted Ventilatory Assist vs. Conventional Mechanical Ventilation in Adults and Children With Acute Respiratory Failure: A Systematic Review and Meta-Analysis.
- Infection and sepsis
- Infection prevention
- Mechanical ventilation
- Medical
- Nursing
- Physiotherapy
- Respiratory
Summary
Systematic review and meta-analysis of 18 studies (926 adult and paediatric patients) comparing neurally adjusted ventilatory assist (NAVA) with conventional mechanical ventilation modes in acute respiratory failure. The primary outcome was the asynchrony index, with secondary outcomes including duration of mechanical ventilation, ICU mortality, ventilator-associated pneumonia, pH and PaCO2. NAVA was associated with reduced patient-ventilator asynchrony and lower ICU mortality, with no significant difference in VAP incidence or gas exchange measures. Useful background for PICU teams considering NAVA, though the pooled population mixes adults and children.
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- Open (Creative Commons)
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