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Guideline · Consensus statement

Ketogenic diet therapy for children with super-refractory status epilepticus in intensive care: International clinical practice recommendations.

Consensus statementInternational consensus group (Epilepsia Open)2026Full text
  • Gastrointestinal and nutrition
  • Medical
  • Neurology
  • Nursing
  • Nutrition
  • Status epilepticus

Summary

First international multidisciplinary consensus recommendations on using ketogenic diet therapy for children with super-refractory status epilepticus in paediatric intensive care. Developed from a literature review of 22 papers plus a survey of 72 multidisciplinary professionals, with consensus set at 75% agreement. Covers patient selection and timing, preparation, dietary prescription, initiation (with a focus on enteral nutrition), monitoring for adverse effects, fine-tuning and weaning. The authors stress early initiation, close monitoring and close collaboration between intensivists, neurologists, dietitians, nurses and pharmacists, while noting most recommendations rest on expert agreement rather than published evidence.

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