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Evidence · Research paper

Impact of the francophone pediatric intensive care group bronchiolitis recommendations on diagnostic testing, antibiotic therapy and patient prognosis.

Research paperArchives de Pédiatrie (Société française de pédiatrie) – study of GFRUP guidelines2026
  • Bronchiolitis
  • Infection and sepsis
  • Infection prevention
  • Medical
  • Nursing
  • Respiratory
  • Sepsis

Summary

A single-centre retrospective study from a French PICU comparing two bronchiolitis epidemic seasons before and after implementation of GFRUP bronchiolitis recommendations. It reports on sepsis incidence, bacterial co-infection, diagnostic test use and antibiotic prescribing in infants admitted with severe bronchiolitis. Fewer additional diagnostic tests and narrower-spectrum antibiotic choices were observed without any increase in sepsis or bacterial infection rates. Of interest to PICU teams for antimicrobial stewardship and guideline implementation, though it is an evaluation study rather than a guideline itself.

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