Evidence · Systematic review or meta-analysis
Association between early bronchiolitis and the development of childhood asthma: a meta-analysis.
- Asthma
- Bronchiolitis
- Medical
- Nursing
- Respiratory
Summary
Systematic review and meta-analysis of 32 cohort and case-control studies (nearly 293 000 children) examining whether bronchiolitis before 2 years of age predicts later wheezing or asthma. The pooled analysis found a substantially increased relative risk of subsequent wheezing/asthma following early bronchiolitis. The authors caution about heterogeneity and residual confounding, calling for standardised prospective studies. Relevant background for PICU teams caring for infants with severe bronchiolitis and counselling families on longer-term respiratory outcomes.
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- Licence:
- Open (Creative Commons)
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