Evidence · Research paper
Haemodialysing babies weighing <8 kg with the Newcastle infant dialysis and ultrafiltration system (Nidus): comparison with peritoneal and conventional haemodialysis.
- Acute kidney injury
- Medical
- Nursing
- Renal and metabolic
- Renal replacement therapy
This paper is from 2014, more than five years ago. Newer evidence may have been published since.
Summary
This study evaluates the Newcastle infant dialysis and ultrafiltration system (Nidus) for haemodialysis in infants weighing under 8 kg, comparing it with peritoneal dialysis and conventional haemodialysis. It combines piglet experiments, a small randomised cross-over element and compassionate-use cases, reporting solute clearances, ultrafiltration precision and safety across several hundred sessions. The authors conclude the device can deliver dialysis without blood priming using single-lumen access in the PICU and outpatient settings. Relevant to PICU teams managing renal replacement therapy in very small infants.
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- Licence:
- Open (Creative Commons)
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