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Evidence · Randomised trial

Effects of Early versus Standard Central Line Removal on the Growth of Preterm Infants with Very Low Birth Weight: A Non-Inferiority, Randomized Clinical Trial.

Randomised trialNutrients (MDPI)2022Full text
  • Care and rehabilitation
  • Gastrointestinal and nutrition
  • Line and device care
  • Medical
  • Nursing
  • Nutrition
  • Professional practice

Summary

A multicentre non-inferiority randomised trial in Polish neonatal intensive care units comparing removal of central lines at an enteral feeding volume of 100 mL/kg/day versus 140 mL/kg/day in very low birth weight preterm infants. The primary outcome was weight at 36 weeks' postmenstrual age, and earlier removal was found non-inferior with no intervention-related adverse events. Relevant to neonatal and paediatric critical care teams weighing central venous access duration against nutritional progression and line-associated risks.

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