Evidence · Randomised trial
In-line filtration in very preterm neonates: a randomized controlled trial.
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This paper is from 2020, more than five years ago. Newer evidence may have been published since.
Summary
Randomised controlled trial in very preterm neonates comparing in-line intravenous filtration with standard care without filters. The primary outcome was change in pro-inflammatory cytokine concentrations between day 3 and day 8, with major neonatal complications as secondary outcomes. No beneficial effect of in-line filtration on inflammatory response or neonatal morbidity was demonstrated. Findings should be read alongside local practices for infusion preparation and central line management.
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