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Evidence · Research paper

Cognitive function following diabetic ketoacidosis in young children with type 1 diabetes.

Research paperEndocrinology, Diabetes & Metabolism (journal)2023Full text
  • DKA
  • Fluids and electrolytes
  • Medical
  • Neurology
  • Nursing
  • Renal and metabolic

Summary

Prospective study of neurocognitive outcomes in 3- to 5-year-olds presenting with DKA at onset of type 1 diabetes, enrolled within a multi-site randomised trial of intravenous fluid protocols, compared with children with T1D and no DKA exposure. Cognitive testing 2-6 months after the episode showed lower IQ scores in DKA-exposed children irrespective of severity, persisting after adjustment for socioeconomic status and ethnicity. Relevant to PICU teams managing paediatric DKA, highlighting potential neurocognitive consequences even after a single, mild episode.

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Open (Creative Commons)

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