Evidence · Systematic review or meta-analysis
Interventions to improve neonatal and infant intubation success: a meta-analysis.
- Airway
- Difficult airway
- Intubation
- Medical
- Non-invasive ventilation and high flow
- Nursing
- Respiratory
Summary
Meta-analysis of 30 randomised studies on interventions improving endotracheal intubation success in neonates and infants, mostly elective intubations in NICU or theatre. Video laryngoscopy improved first-attempt success over direct laryngoscopy with high-certainty evidence and without prolonging intubation time. Pharmacological interventions, particularly neuromuscular blockade and sedatives, generally increased success, with neuromuscular blockade shortening intubation duration. Non-invasive respiratory support during intubation probably improves first-attempt success; desaturation outcomes did not differ.
Summary written for PICUlearn. Always read the original.
- Licence:
- Open (Creative Commons)
The full text of this openly licensed paper is available to PICUlearn members, and Peeky can answer questions from it.
Guidelines are shown for education. Follow your unit's own guidance and senior advice.