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Evidence · Systematic review or meta-analysis

Trends in In-Hospital Cardiac Arrest and Mortality Among Children With Cardiac Disease in the Intensive Care Unit: A Systematic Review and Meta-analysis.

Systematic review or meta-analysisJAMA Network Open2023Full text
  • Arrhythmias
  • Cardiac arrest and resuscitation
  • Cardiovascular
  • Congenital heart disease
  • ECMO
  • Medical
  • Nursing
  • Professional practice

Summary

Systematic review and meta-analysis of 25 observational studies (over 131 000 patients) examining incidence, trends and factors associated with in-hospital cardiac arrest and mortality in children with cardiac disease in intensive care. Pooled data indicate about 5% of cardiac ICU children experience IHCA, with roughly half dying in hospital, and a substantial proportion not achieving return of spontaneous circulation. A minority underwent ECPR in centres with ECMO capability. Both IHCA incidence and associated mortality declined over the preceding two decades, though the authors highlight a need for resuscitation strategies tailored to children with cardiac disease.

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