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Evidence · Randomised trial

Efficacy of Prophylactic Dexmedetomidine in Preventing Postoperative Junctional Ectopic Tachycardia After Pediatric Cardiac Surgery.

Randomised trialJournal of the American Heart Association2017Over 5 years oldFull text
  • Arrhythmias
  • Cardiovascular
  • Congenital heart disease
  • Medical
  • Nursing
  • Sedation
  • Sedation and analgesia

This paper is from 2017, more than five years ago. Newer evidence may have been published since.

Summary

A prospective randomised controlled study of 90 children undergoing elective congenital heart surgery comparing prophylactic dexmedetomidine with placebo. The primary outcome was incidence of postoperative junctional ectopic tachycardia, with secondary outcomes including bradycardia, hypotension, vasoactive inotropic score, ventilation time, unit and hospital stay, and mortality. The authors report a lower incidence of junctional ectopic tachycardia in the dexmedetomidine group without significant adverse effects. Relevant to cardiac PICU teams managing postoperative arrhythmia risk and sedation strategy.

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