Evidence · Other
Priorities for Clinical Research in Pediatric Extracorporeal Membrane Oxygenation Anticoagulation From the Pediatric Extracorporeal Membrane Oxygenation Anticoagulation CollaborativE Consensus Conference.
- Blood products
- Cardiovascular
- ECMO
- Gastrointestinal and nutrition
- Haematology and oncology
- Medical
- Nursing
- Nutrition
- Respiratory
Summary
This paper reports research priorities for anticoagulation and haemostasis management in neonates and children supported on ECMO, derived from the PEACE consensus conference. It follows a systematic review of literature from 1988 to 2021 and serial international, interprofessional consensus meetings, with priorities ranked using the Child Health and Nutrition Research Initiative method. Twenty topics were prioritised across five domains: definitions and outcomes, therapeutics, anticoagulant monitoring, protocolised management, and the effect of the ECMO circuit and its components on haemostasis. It highlights evidence gaps rather than giving prescriptive clinical thresholds.
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- Licence:
- Open (Creative Commons)
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