Evidence · Randomised trial
The minimally effective dose of sucrose for procedural pain relief in neonates: a randomized controlled trial.
- Medical
- Nursing
- Pain management
- Sedation and analgesia
This paper is from 2018, more than five years ago. Newer evidence may have been published since.
Summary
A multicentre Canadian randomised controlled trial in 245 neonates across four tertiary NICUs comparing three volumes of 24% oral sucrose, with non-nutritive sucking, before a routine heel lance. Pain intensity was measured with the Premature Infant Pain Profile-Revised at 30 and 60 seconds, with adverse events as a secondary outcome. No differences in pain scores were found between the dose groups, though pain was not fully abolished, and adverse events were infrequent and self-resolving. Relevant to neonatal and paediatric critical care staff delivering procedural pain management.
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- Licence:
- Open (Creative Commons)
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