Evidence · Systematic review or meta-analysis
Effect of high-flow nasal oxygen therapy on perioperative hypoxemia in children: a systematic review and meta-analysis.
- Airway
- Difficult airway
- Intubation
- Mechanical ventilation
- Medical
- Non-invasive ventilation and high flow
- Nursing
- Respiratory
Summary
Systematic review and meta-analysis of eight randomised trials (653 children) comparing high-flow nasal cannula oxygen with conventional oxygen therapy across the perioperative period, covering anaesthetic induction, intraoperative sedation and post-extubation. HFNC was associated with fewer desaturation events, higher minimum oxygen saturation and less need for additional airway interventions, with no significant difference in safe apnoea time or end transcutaneous CO2. Findings are limited by few studies and heterogeneous clinical settings. Relevant to PICU teams using apnoeic oxygenation and HFNC around intubation, procedural sedation and extubation.
Summary written for PICUlearn. Always read the original.
- Licence:
- Open (Creative Commons)
The full text of this openly licensed paper is available to PICUlearn members, and Peeky can answer questions from it.
Guidelines are shown for education. Follow your unit's own guidance and senior advice.