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Guideline · Consensus statement

Anticoagulation Monitoring and Targets: The Pediatric Extracorporeal Membrane Oxygenation Anticoagulation CollaborativE Consensus Conference.

Consensus statementPediatric ECMO Anticoagulation CollaborativE (PEACE), PCCM/SCCM2024Full text
  • Blood products
  • Cardiovascular
  • ECMO
  • Haematology and oncology
  • Line and device care
  • Medical
  • Nursing

Summary

Consensus statements from the Pediatric ECMO Anticoagulation CollaborativE on which assays to use for anticoagulation monitoring during paediatric ECMO and what targets to aim for. Developed via systematic review to May 2021, GRADE appraisal and a modified Delphi process among 48 experts, yielding one weak recommendation, two consensus statements and three good practice statements. The authors emphasise that paediatric evidence is poor with major gaps, and provide bedside resources for monitoring. Relevant to PICU and ECMO teams managing circuit anticoagulation and bleeding/thrombosis risk.

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