Evidence · Systematic review or meta-analysis
Long-term risk of chronic kidney disease and mortality in children after acute kidney injury: a systematic review.
- Acute kidney injury
- Medical
- Nursing
- Renal and metabolic
- Renal replacement therapy
This paper is from 2014, more than five years ago. Newer evidence may have been published since.
Summary
This systematic review and meta-analysis pools ten paediatric cohort studies examining long-term outcomes following an episode of acute kidney injury in children. Outcomes assessed included proteinuria, hypertension, reduced glomerular filtration rate and mortality, with a mean follow-up of about 6.5 years. The authors report substantial heterogeneity in AKI definitions, study quality and outcome reporting, and no study included a non-AKI comparator group. The findings suggest children who survive AKI may warrant longer-term renal follow-up, though prospective controlled studies are needed.
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- Licence:
- Open (Creative Commons)
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