Evidence · Systematic review or meta-analysis
Risk Factors for Acute Kidney Injury in Critically Ill Neonates: A Systematic Review and Meta-Analysis.
- Acute kidney injury
- Cardiovascular
- Congenital heart disease
- Infection and sepsis
- Mechanical ventilation
- Medical
- Nursing
- Renal and metabolic
- Respiratory
- Sepsis
Summary
Systematic review and meta-analysis of 17 observational studies examining risk factors for acute kidney injury in critically ill neonates. Nine factors were significantly associated with AKI, including lower gestational age and birthweight, lower Apgar scores, congenital heart disease, hyperbilirubinaemia, necrotising enterocolitis, sepsis and mechanical ventilation, while sex, prematurity, caesarean delivery, prenatal haemorrhage and vancomycin exposure were not. Reported AKI incidence varied widely across studies. Useful for neonatal and paediatric intensive care teams considering early risk prediction and prevention of AKI.
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- Open (Creative Commons)
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