Evidence · Systematic review or meta-analysis
Effect of therapeutic hypothermia on renal and myocardial function in asphyxiated (near) term neonates: A systematic review and meta-analysis.
- Acute kidney injury
- Cardiovascular
- Medical
- Neurology
- Nursing
- Renal and metabolic
Summary
A systematic review and meta-analysis of therapeutic hypothermia in (near) term asphyxiated neonates, focusing on renal and myocardial rather than neurological outcomes. Nine studies reported acute kidney injury incidence, with pooled analysis suggesting a reduction in AKI with cooling. Short-term cardiac biomarker, ECG and echocardiographic findings suggested possible cardioprotection, but no studies addressed long-term renal or myocardial function. Relevant to neonatal and paediatric intensive care teams managing cooled asphyxiated infants.
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- Licence:
- Open (Creative Commons)
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