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Evidence · Systematic review or meta-analysis

Endotracheal Tube-Associated Complications in Paediatric Critical Care: A Systematic Review and Meta-Analysis.

Systematic review or meta-analysisNursing in Critical Care2025Full text
  • Airway
  • Care and rehabilitation
  • Infection and sepsis
  • Infection prevention
  • Intubation
  • Line and device care
  • Mechanical ventilation
  • Medical
  • Nursing
  • Physiotherapy
  • Pressure area care
  • Respiratory

Summary

A systematic review and meta-analysis of 34 observational studies and RCTs (over 50 000 children, 232 123 ventilator days) estimating the incidence of endotracheal tube-associated complications in mechanically ventilated children in PICU. Ventilator-associated pneumonia was the most frequent complication, followed by accidental extubation, tube-related pressure injuries and tube blockage, with higher infection rates in low- and middle-income settings. Heterogeneity between studies was substantial. The authors argue these complications represent avoidable harm and call for prevention initiatives, particularly relevant to bedside nursing airway care.

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